Generation of iPSC lines from primary human chorionic villi cells
نویسندگان
چکیده
منابع مشابه
Prenatal Diagnosis, Sampling of Chorionic Villi
Prenatal diagnosis with application of the Amniotic fluid (Amniocentesis: AC) and chorionic villi sampling {CVS) is a general aspect of application in Human Genetics which facilitate the diagnosis of different Genetic defects, enclosing chromosomal abnormalities and Genosomopathies. Diagnosis of Genetic defects for AC and CVS is between 16-20th and 8-12th weeks of gestation respectively. Allica...
متن کاملOutcome of pregnancies with trisomy 2 cells in chorionic villi.
OBJECTIVE To describe the outcome of pregnancies with trisomy 2 in cultures of first-trimester chorionic villous samples (CVS) and determine whether amniocentesis is necessary in the management of such cases. METHODS Cultures of chorionic villi were performed at 11-13 weeks in 37 474 pregnancies. In those with trisomy 2 cells, amniocentesis was performed at 16 weeks. Pregnancy outcome was obt...
متن کاملImmunocytochemical identification of cytotrophoblast from other mononuclear cell populations isolated from first-trimester human chorionic villi.
Trophoblast biologists are often uncertain as to what cell types they are investigating because the mononuclear cell populations prepared from trypsinization of human first-trimester chorionic villi are morphologically very similar. In the present study, immunocytochemical and phagocytic markers have been used to distinguish cytotrophoblast populations from cell types derived from the mesenchym...
متن کاملEffects of hypoxia on heme oxygenase expression in human chorionic villi explants and immortalized trophoblast cells.
Although hypoxia induces heme oxygenase (HO)-1 protein and mRNA expression in many cell types, hypoxia has also been shown to decrease HO-1 mRNA and protein expression. We tested the hypothesis that 24-h preexposure to hypoxia in human placental preparations suppresses HO protein expression and enzymatic function. Immortalized HTR-8/SVneo first-trimester trophoblast cells and explants of normal...
متن کاملUniversity of Groningen Mesenchymal stem cells in human placental chorionic villi reside in a vascular Niche
The chorionic villi of human term placentae are a rich source of mesenchymal stem cells (PMSCs). The stem cell ‘‘niche’’ within the chorionic villi regulates how PMSCs participate in placental tissue generation, maintenance and repair, but the anatomic location of the niche has not been defined. A number of cell surface markers for phenotypic characterisation of mesenchymal stem cells (MSCs) we...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Stem Cell Research
سال: 2015
ISSN: 1873-5061
DOI: 10.1016/j.scr.2015.10.011